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Gene: NDP (norrin cystine knot growth factor NDP) Homo sapiens
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Symbol: NDP
Name: norrin cystine knot growth factor NDP
Description: Exhibits cytokine activity; frizzled binding activity; and protein homodimerization activity. Involved in Norrin signaling pathway and positive regulation of transcription, DNA-templated. Localizes to the cell surface; collagen-containing extracellular matrix; and extracellular space. Implicated in Norrie disease; exudative vitreoretinopathy; and retinopathy of prematurity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EVR2; exudative vitreoretinopathy 2 (X-linked); FEVR; ND; NDP, norrin cystine knot growth factor; Norrie disease (pseudoglioma); norrie disease protein; norrin; X-linked exudative vitreoretinopathy 2 protein
Orthologs:
Mus musculus (house mouse) : Ndp (Norrie disease (pseudoglioma) (human))  MGI  Alliance
Rattus norvegicus (Norway rat) : Ndp (norrin cystine knot growth factor NDP)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ndp (norrin cystine knot growth factor NDP)
Pan paniscus (bonobo/pygmy chimpanzee) : NDP (norrin cystine knot growth factor NDP)
Canis lupus familiaris (dog) : NDP (norrin cystine knot growth factor NDP)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ndp (norrin cystine knot growth factor NDP)
Sus scrofa (pig) : NDP (norrin cystine knot growth factor NDP)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X43,948,776 - 43,973,390 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X43,808,022 - 43,832,921 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X43,692,966 - 43,717,788 (-)NCBINCBI36hg18NCBI36
Build 34X43,564,279 - 43,589,004NCBI
CeleraX47,947,782 - 47,972,683 (-)NCBI
Cytogenetic MapXp11.3NCBI
HuRefX41,537,322 - 41,562,014 (-)NCBIHuRef
CHM1_1X43,841,148 - 43,866,049 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NDP
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343189
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.