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Gene: H2BC21 (H2B clustered histone 21) Homo sapiens
Symbol: H2BC21
Name: H2B clustered histone 21
Description: Predicted to have DNA binding activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide and defense response to other organism. Localizes to cytosol; extracellular space; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GL105; H2B; H2B histone family, member Q; H2B.1; H2BE; H2BFQ; H2BGL105; H2BQ; HIST2H2BE; histone 2, H2be; histone cluster 2 H2B family member e; histone cluster 2, H2be; histone H2B type 2-E; histone H2B-GL105; histone H2B.q; MGC119802; MGC119804; MGC129733; MGC129734
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100985433 (histone H2B type 2-E)
Canis lupus familiaris (dog) : H2BC20 (H2B clustered histone 20)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101967584 (histone H2B type 2-E)
Sus scrofa (pig) : LOC100738744 (histone H2B type 2-E)
Chlorocebus sabaeus (African green monkey) : HIST2H2BE (histone cluster 2 H2B family member e)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1149,884,459 - 149,886,652 (-)EnsemblGRCh38hg38GRCh38
GRCh381149,884,459 - 149,886,682 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371149,856,010 - 149,858,232 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361148,122,634 - 148,124,856 (-)NCBINCBI36hg18NCBI36
Build 341146,669,082 - 146,671,305NCBI
Celera1122,972,235 - 122,974,457 (-)NCBI
Cytogenetic Map1q21.2NCBI
HuRef1121,236,878 - 121,239,100 (-)NCBIHuRef
CHM1_11151,252,586 - 151,254,808 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on H2BC21
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343213
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.