Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: MAGEA5 (MAGE family member A5) Homo sapiens
Analyze
Symbol: MAGEA5
Name: MAGE family member A5
Description: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene. The protein is represented in this Gene record in accordance with the assumed protein-coding status defined in the literature. Read-through transcription exists between this gene and the upstream melanoma antigen family A, 10 (MAGEA10) gene. [provided by RefSeq, Oct 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen 1.5; cancer/testis antigen family 1, member 5; CT1.5; MAGE-5 antigen; MAGE-5a antigen; MAGE-5b antigen; MAGE5; MAGEA4; melanoma antigen family A, 5; melanoma antigen family A5; melanoma-associated antigen 5; MGC129526
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X152,114,049 - 152,117,939 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X151,282,521 - 151,286,411 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X151,033,182 - 151,037,100 (-)NCBINCBI36hg18NCBI36
Build 34X150,953,096 - 150,957,012NCBI
CeleraX151,528,019 - 151,531,937 (-)NCBI
Cytogenetic MapXq28NCBI
HuRefX140,136,510 - 140,140,395 (-)NCBIHuRef
CHM1_1X151,157,289 - 151,161,174 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MAGEA5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343521
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.