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Gene: KDM3B (lysine demethylase 3B) Homo sapiens
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Symbol: KDM3B
Name: lysine demethylase 3B
CRRD ID: 1343523
Description: Predicted to have chromatin DNA binding activity; histone demethylase activity (H3-K9 specific); and transcription coregulator activity. Predicted to be involved in histone H3-K9 demethylation and regulation of transcription by RNA polymerase II. Localizes to nucleoplasm. Biomarker of acute lymphoblastic leukemia; breast cancer; colorectal cancer; and lung non-small cell carcinoma; PARTICIPATES IN histone modification pathway; INTERACTS WITH aflatoxin B1; benzo[a]pyrene; benzo[a]pyrene diol epoxide I.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5qNCA; [histone H3]-dimethyl-L-lysine(9) demethylase 3B; C5orf7; DIJOS; jmjC domain-containing histone demethylation protein 2B; JMJD1B; jumonji domain containing 1B; jumonji domain-containing protein 1B; KIAA1082; lysine (K)-specific demethylase 3B; lysine-specific demethylase 3B; NET22; nuclear protein 5qNCA
Orthologs:
Mus musculus (house mouse) : Kdm3b (KDM3B lysine (K)-specific demethylase 3B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Kdm3b (lysine demethylase 3B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm3b (lysine demethylase 3B)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM3B (lysine demethylase 3B)
Canis lupus familiaris (dog) : KDM3B (lysine demethylase 3B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm3b (lysine demethylase 3B)
Sus scrofa (pig) : KDM3B (lysine demethylase 3B)
Chlorocebus sabaeus (African green monkey) : KDM3B (lysine demethylase 3B)
Heterocephalus glaber (naked mole-rat) : Kdm3b (lysine demethylase 3B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5138,352,685 - 138,437,028 (+)EnsemblGRCh38hg38GRCh38
GRCh385138,352,685 - 138,437,027 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375137,688,285 - 137,772,716 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365137,716,184 - 137,800,615 (+)NCBINCBI36hg18NCBI36
Build 345137,716,183 - 137,800,616NCBI
Celera5133,809,116 - 133,893,549 (+)NCBI
Cytogenetic Map5q31.2NCBI
HuRef5132,879,205 - 132,963,497 (+)NCBIHuRef
CHM1_15137,121,010 - 137,205,439 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KDM3B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343523
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.