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Gene: VCX (variable charge X-linked) Homo sapiens
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Symbol: VCX
Name: variable charge X-linked
Description: This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 10 repeats of the 30-bp unit. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC118975; variable charge protein on X with ten repeats; variable charge X-linked protein 1; variable charge, X chromosome; variable charge, X-linked; variably charged protein X-B1; VCX-10r; VCX-B1; VCX1; VCX10R; VCXB1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X7,842,262 - 7,844,143 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X7,810,303 - 7,812,184 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X7,770,303 - 7,772,184 (+)NCBINCBI36hg18NCBI36
Build 34X8,243,201 - 8,244,286NCBI
CeleraX11,985,704 - 11,987,525 (+)NCBI
Cytogenetic MapXp22.31NCBI
HuRefX5,618,278 - 5,619,639 (+)NCBIHuRef
CHM1_1X7,791,239 - 7,792,969 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on VCX
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343537
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.