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Gene: TNFRSF12A (TNF receptor superfamily member 12A) Homo sapiens
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Symbol: TNFRSF12A
Name: TNF receptor superfamily member 12A
Description: Involved in positive regulation of extrinsic apoptotic signaling pathway and regulation of wound healing. Predicted to localize to the plasma membrane; INTERACTS WITH (-)-citrinin; (-)-epigallocatechin 3-gallate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD266; FGF-inducible 14; fibroblast growth factor-inducible immediate-early response protein 14; FN14; tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily, member 12A; tweak-receptor; TWEAKR; type I transmembrane protein Fn14
Orthologs:
Mus musculus (house mouse) : Tnfrsf12a (tumor necrosis factor receptor superfamily, member 12a)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tnfrsf12a (TNF receptor superfamily member 12A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfrsf12a (TNF receptor superfamily member 12A)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFRSF12A (TNF receptor superfamily member 12A)
Canis lupus familiaris (dog) : TNFRSF12A (TNF receptor superfamily member 12A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfrsf12a (TNF receptor superfamily member 12A)
Sus scrofa (pig) : TNFRSF12A (TNF receptor superfamily member 12A)
Chlorocebus sabaeus (African green monkey) : TNFRSF12A (TNF receptor superfamily member 12A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl163,018,445 - 3,022,383 (+)Ensembl
GRCh38163,020,368 - 3,022,383 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37163,070,313 - 3,072,384 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36163,010,361 - 3,012,385 (+)NCBINCBI36hg18NCBI36
Build 34163,010,360 - 3,012,382NCBI
Celera163,275,870 - 3,277,940 (+)NCBI
Cytogenetic Map16p13.3NCBI
HuRef163,042,784 - 3,043,958 (+)NCBIHuRef
CHM1_1163,070,187 - 3,072,258 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TNFRSF12A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343569
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.