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Gene: KLRF1 (killer cell lectin like receptor F1) Homo sapiens
Symbol: KLRF1
Name: killer cell lectin like receptor F1
Description: Predicted to have MHC class I receptor activity. Predicted to be involved in cell surface receptor signaling pathway and regulation of immune response. Predicted to localize to integral component of plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: activating coreceptor NKp80; C-type lectin domain family 5 member C; CLEC5C; killer cell lectin-like receptor F1; killer cell lectin-like receptor subfamily F member 1; killer cell lectin-like receptor subfamily F, member 1; lectin-like receptor F1; MGC119907; MGC119908; MGC119909; NKp80
Rattus norvegicus (Norway rat) : Klrb1 (killer cell lectin like receptor B1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : KLRF1 (killer cell lectin like receptor F1)
Canis lupus familiaris (dog) : KLRF1 (killer cell lectin like receptor F1)
Sus scrofa (pig) : KLRF1 (killer cell lectin like receptor F1)
Chlorocebus sabaeus (African green monkey) : KLRF1 (killer cell lectin like receptor F1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl129,827,481 - 9,845,007 (+)EnsemblGRCh38hg38GRCh38
GRCh38129,800,052 - 9,845,005 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37129,980,038 - 9,997,604 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36129,871,344 - 9,888,871 (+)NCBINCBI36hg18NCBI36
Build 34129,871,343 - 9,888,868NCBI
Celera1215,141,454 - 15,158,976 (+)NCBI
Cytogenetic Map12p13.31NCBI
HuRef129,723,009 - 9,740,531 (+)NCBIHuRef
CHM1_1129,949,031 - 9,966,573 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KLRF1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343603
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.