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Gene: ACKR3 (atypical chemokine receptor 3) Homo sapiens
Symbol: ACKR3
Name: atypical chemokine receptor 3
Description: Exhibits C-X-C chemokine binding activity; C-X-C chemokine receptor activity; and scavenger receptor activity. Involved in chemokine-mediated signaling pathway; receptor internalization; and regulation of intracellular signal transduction. Localizes to several cellular components, including the cell surface; clathrin-coated pit; and endosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C-X-C chemokine receptor type 7; chemokine (C-X-C motif) receptor 7; chemokine orphan receptor 1; CMKOR1; CXC-R7; CXCR-7; CXCR7; G protein-coupled receptor; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; GPR159; RDC-1; RDC1
Mus musculus (house mouse) : Ackr3 (atypical chemokine receptor 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ackr3 (atypical chemokine receptor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ackr3 (atypical chemokine receptor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ACKR3 (atypical chemokine receptor 3)
Canis lupus familiaris (dog) : ACKR3 (atypical chemokine receptor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ackr3 (atypical chemokine receptor 3)
Sus scrofa (pig) : ACKR3 (atypical chemokine receptor 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2236,567,787 - 236,582,354 (+)Ensembl
GRCh382236,537,131 - 236,582,358 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372237,469,424 - 237,491,001 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,143,119 - 237,155,736 (+)NCBINCBI36hg18NCBI36
Build 342237,260,442 - 237,272,991NCBI
Celera2231,191,070 - 231,203,687 (+)NCBI
Cytogenetic Map2q37.3NCBI
HuRef2229,272,353 - 229,284,798 (+)NCBIHuRef
CHM1_12237,484,219 - 237,496,832 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ACKR3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343702
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.