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Gene: PDYN (prodynorphin) Homo sapiens
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Symbol: PDYN
Name: prodynorphin
Description: Predicted to have opioid receptor binding activity. Predicted to be involved in chemical synaptic transmission; neuropeptide signaling pathway; and sensory perception. Localizes to plasma membrane. Implicated in spinocerebellar ataxia type 23 and temporal lobe epilepsy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADCA; beta-neoendorphin; beta-neoendorphin-dynorphin; dynorphin; leu-enkephalin; leumorphin; MGC26418; neoendorphin-dynorphin-enkephalin prepropeptide; PENKB; preprodynorphin; preproenkephalin B; proenkephalin-B; rimorphin; SCA23; spinocerebellar ataxia 23
Orthologs:
Mus musculus (house mouse) : Pdyn (prodynorphin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pdyn (prodynorphin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdyn (prodynorphin)
Pan paniscus (bonobo/pygmy chimpanzee) : PDYN (prodynorphin)
Canis lupus familiaris (dog) : PDYN (prodynorphin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdyn (prodynorphin)
Sus scrofa (pig) : PDYN (prodynorphin)
Chlorocebus sabaeus (African green monkey) : PDYN (prodynorphin)
Heterocephalus glaber (naked mole-rat) : Pdyn (prodynorphin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl201,978,757 - 1,994,285 (-)EnsemblGRCh38hg38GRCh38
GRCh38201,978,756 - 1,994,285 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37201,959,402 - 1,974,931 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36201,907,402 - 1,922,702 (-)NCBINCBI36hg18NCBI36
Build 34201,907,402 - 1,922,702NCBI
Celera202,023,375 - 2,038,860 (-)NCBI
Cytogenetic Map20p13NCBI
HuRef201,909,347 - 1,924,873 (-)NCBIHuRef
CHM1_1201,959,620 - 1,975,149 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PDYN
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343954
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.