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Gene: HACD1 (3-hydroxyacyl-CoA dehydratase 1) Homo sapiens
Symbol: HACD1
Name: 3-hydroxyacyl-CoA dehydratase 1
CRRD ID: 1343988
Description: Exhibits 3-hydroxyacyl-CoA dehydratase activity; enzyme binding activity; and hydroxyapatite binding activity. Involved in several processes, including cementum mineralization; fatty acid biosynthetic process; and positive regulation of cell-substrate adhesion. Localizes to endoplasmic reticulum.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CAP; cementum attachment protein; protein-tyrosine phosphatase-like member A; PTPLA; very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 1; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1
Mus musculus (house mouse) : Hacd1 (3-hydroxyacyl-CoA dehydratase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hacd1 (3-hydroxyacyl-CoA dehydratase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hacd1 (3-hydroxyacyl-CoA dehydratase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HACD1 (3-hydroxyacyl-CoA dehydratase 1)
Canis lupus familiaris (dog) : HACD1 (3-hydroxyacyl-CoA dehydratase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hacd1 (3-hydroxyacyl-CoA dehydratase 1)
Sus scrofa (pig) : HACD1 (3-hydroxyacyl-CoA dehydratase 1)
Chlorocebus sabaeus (African green monkey) : HACD1 (3-hydroxyacyl-CoA dehydratase 1)
Heterocephalus glaber (naked mole-rat) : Hacd1 (3-hydroxyacyl-CoA dehydratase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1017,589,032 - 17,617,374 (-)EnsemblGRCh38hg38GRCh38
GRCh381017,589,032 - 17,617,374 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371017,631,031 - 17,659,383 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361017,671,964 - 17,699,379 (-)NCBINCBI36hg18NCBI36
Build 341017,672,275 - 17,699,379NCBI
Celera1017,565,146 - 17,593,075 (-)NCBI
Cytogenetic Map10p12.33NCBI
HuRef1017,544,972 - 17,572,460 (-)NCBIHuRef
CHM1_11017,632,313 - 17,659,761 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on HACD1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1343988
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.