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Gene: POLE3 (DNA polymerase epsilon 3, accessory subunit) Homo sapiens
Symbol: POLE3
Name: DNA polymerase epsilon 3, accessory subunit
Description: Predicted to have chromatin DNA binding activity. Involved in histone H3 acetylation. Localizes to Ada2/Gcn5/Ada3 transcription activator complex and epsilon DNA polymerase complex.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: arsenic transactivated protein; arsenic-transactivated protein; asTP; CHARAC17; CHRAC-17; CHRAC17; CHRAC2; chromatin accessibility complex 17 kDa protein; chromatin accessibility complex subunit 2; DNA polymerase epsilon p17 subunit; DNA polymerase epsilon subunit 3; DNA polymerase epsilon subunit p17; DNA polymerase II subunit 3; histone fold protein CHRAC17; huCHRAC17; p17; polymerase (DNA directed), epsilon 3 (p17 subunit); polymerase (DNA directed), epsilon 3, accessory subunit; polymerase (DNA) epsilon 3, accessory subunit; YBL1
Mus musculus (house mouse) : Pole3 (polymerase (DNA directed), epsilon 3 (p17 subunit))  MGI  Alliance
Rattus norvegicus (Norway rat) : Pole3 (DNA polymerase epsilon 3, accessory subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pole3 (DNA polymerase epsilon 3, accessory subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : POLE3 (DNA polymerase epsilon 3, accessory subunit)
Canis lupus familiaris (dog) : POLE3 (DNA polymerase epsilon 3, accessory subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pole3 (DNA polymerase epsilon 3, accessory subunit)
Sus scrofa (pig) : POLE3 (DNA polymerase epsilon 3, accessory subunit)
Chlorocebus sabaeus (African green monkey) : POLE3 (DNA polymerase epsilon 3, accessory subunit)
Heterocephalus glaber (naked mole-rat) : Pole3 (DNA polymerase epsilon 3, accessory subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl9113,407,235 - 113,410,675 (-)EnsemblGRCh38hg38GRCh38
GRCh389113,407,235 - 113,410,749 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379116,169,515 - 116,173,029 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369115,209,342 - 115,212,773 (-)NCBINCBI36hg18NCBI36
Build 349113,249,074 - 113,252,506NCBI
Celera986,817,115 - 86,820,629 (-)NCBI
Cytogenetic Map9q32NCBI
HuRef985,776,442 - 85,779,955 (-)NCBIHuRef
CHM1_19116,316,144 - 116,319,658 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on POLE3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1344068
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.