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Gene: CD99 (CD99 molecule (Xg blood group)) Homo sapiens
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Symbol: CD99
Name: CD99 molecule (Xg blood group)
Description: The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 12E7; antigen identified by monoclonal 12E7, Y homolog; antigen identified by monoclonal antibodies 12E7, F21 and O13; CD99 antigen; CD99 molecule; cell surface antigen 12E7; cell surface antigen HBA-71; cell surface antigen O13; E2 antigen; HBA71; MIC2; MIC2 (monoclonal antibody 12E7); MIC2X; MIC2Y; MSK5X; surface antigen MIC2; T-cell surface glycoprotein E2
Orthologs:
Mus musculus (house mouse) : Cd99 (CD99 antigen)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd99 (CD99 molecule (Xg blood group))  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd99 (CD99 molecule (Xg blood group))
Pan paniscus (bonobo/pygmy chimpanzee) : CD99 (CD99 molecule (Xg blood group))
Canis lupus familiaris (dog) : CD99 (CD99 molecule)
Sus scrofa (pig) : CD99 (CD99 molecule (Xg blood group))
more info ...
Related Pseudogenes: CD99P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38Y2,691,133 - 2,741,309 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38X2,691,133 - 2,741,309 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37Y2,559,228 - 2,609,350 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh37X2,609,228 - 2,659,350 (+)ENTREZGENEGRCh37GRCh37hg19GRCh37
Build 36X2,619,228 - 2,669,350 (+)NCBINCBI36hg18NCBI36
Build 36Y2,619,228 - 2,669,350 (+)NCBINCBI36hg18NCBI36
Build 34Y2,602,588 - 2,652,709NCBI
CeleraX6,889,623 - 6,939,779 (+)NCBI
Cytogenetic MapXp22.33 and Yp11.2NCBI
HuRefX550,662 - 601,242 (+)NCBIHuRef
CHM1_1X2,639,530 - 2,689,681 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CD99
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1344139
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.