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Gene: NR1I3 (nuclear receptor subfamily 1 group I member 3) Homo sapiens
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Symbol: NR1I3
Name: nuclear receptor subfamily 1 group I member 3
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to the nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CAR; CAR1; constitutive activator of retinoid response; constitutive active receptor; constitutive active response; constitutive androstane nuclear receptor variant 2; constitutive androstane nuclear receptor variant 3; constitutive androstane nuclear receptor variant 4; constitutive androstane nuclear receptor variant 5; constitutive androstane receptor; MB67; MGC150433; MGC97144; MGC97209; nuclear receptor subfamily 1, group I, member 3; orphan nuclear hormone receptor; orphan nuclear receptor MB67
Orthologs:
Mus musculus (house mouse) : Nr1i3 (nuclear receptor subfamily 1, group I, member 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nr1i3 (nuclear receptor subfamily 1, group I, member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr1i3 (nuclear receptor subfamily 1 group I member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NR1I3 (nuclear receptor subfamily 1 group I member 3)
Canis lupus familiaris (dog) : NR1I3 (nuclear receptor subfamily 1 group I member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr1i3 (nuclear receptor subfamily 1 group I member 3)
Sus scrofa (pig) : NR1I3 (nuclear receptor subfamily 1 group I member 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,229,666 - 161,238,623 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371161,199,456 - 161,208,432 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,466,080 - 159,474,624 (-)NCBINCBI36hg18NCBI36
Build 341158,012,527 - 158,021,028NCBI
Celera1134,266,598 - 134,275,155 (-)NCBI
Cytogenetic Map1q23.3NCBI
HuRef1132,556,384 - 132,564,950 (-)NCBIHuRef
CHM1_11162,595,690 - 162,604,231 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NR1I3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1344163
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.