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Gene: GLI1 (GLI family zinc finger 1) Homo sapiens
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Symbol: GLI1
Name: GLI family zinc finger 1
CRRD ID: 1344225
Description: Exhibits RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and chromatin binding activity. Involved in several processes, including positive regulation of cardiac muscle cell proliferation; positive regulation of macromolecule biosynthetic process; and regulation of signal transduction. Localizes to cytosol and nucleoplasm. Biomarker of multiple sclerosis; nevoid basal cell carcinoma syndrome; and spina bifida.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GLI; GLI-Kruppel family member GLI1; glioma-associated oncogene 1; glioma-associated oncogene family zinc finger 1; glioma-associated oncogene homolog 1 (zinc finger protein); oncogene GLI; PAPA8; PPD1; zinc finger protein GLI1
Orthologs:
Mus musculus (house mouse) : Gli1 (GLI-Kruppel family member GLI1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gli1 (GLI family zinc finger 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gli1 (GLI family zinc finger 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GLI1 (GLI family zinc finger 1)
Canis lupus familiaris (dog) : GLI1 (GLI family zinc finger 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gli1 (GLI family zinc finger 1)
Sus scrofa (pig) : GLI1 (GLI family zinc finger 1)
Chlorocebus sabaeus (African green monkey) : GLI1 (GLI family zinc finger 1)
Heterocephalus glaber (naked mole-rat) : Gli1 (GLI family zinc finger 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1257,459,785 - 57,472,268 (+)EnsemblGRCh38hg38GRCh38
GRCh381257,459,785 - 57,472,451 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371257,853,918 - 57,866,051 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,140,201 - 56,152,312 (+)NCBINCBI36hg18NCBI36
Build 341256,140,200 - 56,152,312NCBI
Celera1257,507,905 - 57,520,038 (+)NCBI
Cytogenetic Map12q13.3NCBI
HuRef1254,891,792 - 54,903,925 (+)NCBIHuRef
CHM1_11257,822,031 - 57,834,164 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GLI1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1344225
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-11-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.