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Gene: H2AB3 (H2A.B variant histone 3) Homo sapiens
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Symbol: H2AB3
Name: H2A.B variant histone 3
Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the most telomeric copy. [provided by RefSeq, Oct 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H2A Barr body-deficient; H2A histone family member B3; H2A histone family, member B3; H2A.Bbd; H2ABBD; H2AFB; H2AFB2; H2AFB3; histone H2A-Bbd type 2/3; histone variant H2A, Barr-body deficient
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X155,459,419 - 155,459,935 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X154,689,080 - 154,689,596 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X154,342,274 - 154,342,790 (-)NCBINCBI36hg18NCBI36
Build 34X154,252,785 - 154,253,300NCBI
CeleraX154,271,936 - 154,272,452 (+)NCBI
Cytogenetic MapXq28NCBI
HuRefX143,154,557 - 143,155,073 (+)NCBIHuRef
CHM1_1X154,600,696 - 154,600,958 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on H2AB3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1344236
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.