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Gene: COX7B (cytochrome c oxidase subunit 7B) Homo sapiens
Symbol: COX7B
Name: cytochrome c oxidase subunit 7B
Description: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIb, which is highly similar to bovine COX VIIb protein and is found in all tissues. This gene may have several pseudogenes on chromosomes 1, 2, 20 and 22. [provided by RefSeq, Jun 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APLCC; cytochrome c oxidase polypeptide VIIb; cytochrome c oxidase subunit 7B, mitochondrial; cytochrome c oxidase subunit VIIb; cytochrome-c oxidase chain VIIb; LSDMCA2
Mus musculus (house mouse) : Cox7b (cytochrome c oxidase subunit 7B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cox7b (cytochrome c oxidase subunit 7B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102020494 (cytochrome c oxidase subunit 7B, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100986707 (cytochrome c oxidase subunit 7B, mitochondrial)
Canis lupus familiaris (dog) : LOC100684983 (cytochrome c oxidase subunit 7B, mitochondrial)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101967130 (cytochrome c oxidase subunit 7B, mitochondrial)
Sus scrofa (pig) : LOC100516480 (cytochrome c oxidase subunit 7B, mitochondrial)
more info ...
Related Pseudogenes: COX7BP1   COX7BP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X77,899,464 - 77,905,384 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X77,154,961 - 77,160,881 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X77,041,617 - 77,047,537 (+)NCBINCBI36hg18NCBI36
Build 34X76,961,105 - 76,967,026NCBI
CeleraX77,395,826 - 77,401,746 (+)NCBI
Cytogenetic MapXq21.1NCBI
HuRefX70,740,654 - 70,746,809 (+)NCBIHuRef
CHM1_1X77,047,649 - 77,053,569 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on COX7B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1344241
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.