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Gene: ARX (aristaless related homeobox) Homo sapiens
Symbol: ARX
Name: aristaless related homeobox
CRRD ID: 1344380
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Predicted to be involved in nervous system development and regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin. Implicated in Partington syndrome; early infantile epileptic encephalopathy 1; lissencephaly; and syndromic X-linked intellectual disability Hedera type.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: aristaless-related homeobox; aristaless-related homeobox, X-linked; cancer/testis antigen 121; CT121; EIEE1; homeobox protein ARX; ISSX; mental retardation, X-linked 29; mental retardation, X-linked 32; mental retardation, X-linked 33; mental retardation, X-linked 36; mental retardation, X-linked 38; mental retardation, X-linked 43; mental retardation, X-linked 54; mental retardation, X-linked 76; MRX29; MRX32; MRX33; MRX36; MRX38; MRX43; MRX54; MRX76; MRX87; MRXS1; PRTS
Mus musculus (house mouse) : Arx (aristaless related homeobox)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arx (aristaless related homeobox)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arx (aristaless related homeobox)
Pan paniscus (bonobo/pygmy chimpanzee) : ARX (aristaless related homeobox)
Canis lupus familiaris (dog) : ARX (aristaless related homeobox)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arx (aristaless related homeobox)
Sus scrofa (pig) : ARX (aristaless related homeobox)
Chlorocebus sabaeus (African green monkey) : ARX (aristaless related homeobox)
Heterocephalus glaber (naked mole-rat) : Arx (aristaless related homeobox)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 EnsemblX25,003,694 - 25,016,420 (-)EnsemblGRCh38hg38GRCh38
GRCh38X25,003,694 - 25,015,965 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X25,021,811 - 25,034,065 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X24,932,213 - 24,943,775 (-)NCBINCBI36hg18NCBI36
Build 34X24,781,948 - 24,793,511NCBI
CeleraX29,145,744 - 29,157,998 (-)NCBI
Cytogenetic MapXp21.3NCBI
HuRefX22,763,568 - 22,793,924 (-)NCBIHuRef
CHM1_1X25,053,346 - 25,065,599 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ARX
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1344380
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-10-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.