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Gene: F5 (coagulation factor V) Homo sapiens
Symbol: F5
Name: coagulation factor V
CRRD ID: 1344593
Description: Predicted to have copper ion binding activity. Predicted to be involved in blood circulation and blood coagulation. Localizes to extracellular vesicle and membrane. Implicated in several diseases, including artery disease (multiple); end stage renal disease; factor V deficiency; liver disease (multiple); and non-arteritic anterior ischemic optic neuropathy. Biomarker of hepatitis; liver cirrhosis; and portal hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: activated protein c cofactor; coagulation factor V (proaccelerin, labile factor); coagulation factor V jinjiang A2 domain; factor V Leiden; FVL; PCCF; proaccelerin, labile factor; RPRGL1; THPH2
Mus musculus (house mouse) : F5 (coagulation factor V)  MGI  Alliance
Rattus norvegicus (Norway rat) : F5 (coagulation factor V)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F5 (coagulation factor V)
Pan paniscus (bonobo/pygmy chimpanzee) : F5 (coagulation factor V)
Canis lupus familiaris (dog) : F5 (coagulation factor V)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F5 (coagulation factor V)
Sus scrofa (pig) : F5 (coagulation factor V)
Chlorocebus sabaeus (African green monkey) : F5 (coagulation factor V)
Heterocephalus glaber (naked mole-rat) : F5 (coagulation factor V)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1169,511,951 - 169,586,588 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1169,511,953 - 169,586,588 (-)EnsemblGRCh38hg38GRCh38
GRCh381169,511,951 - 169,586,630 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371169,481,192 - 169,555,769 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361167,747,816 - 167,822,393 (-)NCBINCBI36hg18NCBI36
Build 341166,215,066 - 166,287,379NCBI
Celera1142,590,970 - 142,665,548 (-)NCBI
Cytogenetic Map1q24.2NCBI
HuRef1140,703,881 - 140,778,453 (-)NCBIHuRef
CHM1_11170,903,222 - 170,977,927 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants