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Gene: NAT1 (N-acetyltransferase 1) Homo sapiens
Symbol: NAT1
Name: N-acetyltransferase 1
Description: Predicted to have arylamine N-acetyltransferase activity. Predicted to be involved in xenobiotic metabolic process. Predicted to localize to cytosol. Implicated in allergic contact dermatitis; carcinoma (multiple); occupational dermatitis; pancreatic cancer; and prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AAC1; arylamide acetylase 1; arylamine N-acetyltransferase 1; MNAT; monomorphic arylamine N-acetyltransferase; N-acetyltransferase 1 (arylamine N-acetyltransferase); N-acetyltransferase type 1; NAT-1; NATI
Mus musculus (house mouse) : Nat1 (N-acetyl transferase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nat1 (N-acetyltransferase 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : NAT1 (N-acetyltransferase 1)
Sus scrofa (pig) : LOC100511905 (arylamine N-acetyltransferase 1)
Chlorocebus sabaeus (African green monkey) : NAT1 (N-acetyltransferase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: Loci in other organisms that are functionally homologous to this one are validly referred to as both NAT1 and NAT2; i.e., the functional homologs of NAT1 include mouse and rat Nat2, while the functional homologs of human NAT2 include mouse and rat Nat1. Name:sequence associations are consistent with current use in the field. [13 Feb 2013]
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl818,170,477 - 18,223,689 (+)EnsemblGRCh38hg38GRCh38
GRCh38818,170,419 - 18,223,689 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37818,027,971 - 18,081,198 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36818,111,895 - 18,125,100 (+)NCBINCBI36hg18NCBI36
Build 34818,111,894 - 18,125,099NCBI
Celera817,033,182 - 17,047,129 (+)NCBI
Cytogenetic Map8p22NCBI
HuRef816,572,274 - 16,625,520 (+)NCBIHuRef
CHM1_1818,229,426 - 18,282,651 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NAT1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1344668
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.