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Gene: GK (glycerol kinase) Homo sapiens
Symbol: GK
Name: glycerol kinase
Description: The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP:glycerol 3-phosphotransferase; GK1; GKD; glycerokinase
Mus musculus (house mouse) : Gk (glycerol kinase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gk (glycerol kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gk (glycerol kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : GK (glycerol kinase)
Canis lupus familiaris (dog) : GK (glycerol kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gk (glycerol kinase)
Sus scrofa (pig) : GK (glycerol kinase)
more info ...
Related Pseudogenes: GK3P   GK4P   GK6P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X30,653,348 - 30,731,462 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X30,671,476 - 30,749,579 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X30,581,461 - 30,658,646 (+)NCBINCBI36hg18NCBI36
Build 34X30,431,196 - 30,508,381NCBI
CeleraX34,794,970 - 34,872,746 (+)NCBI
Cytogenetic MapXp21.2NCBI
HuRefX28,409,908 - 28,487,802 (+)NCBIHuRef
CHM1_1X30,702,368 - 30,780,409 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GK
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1344759
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.