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Gene: UBQLN4 (ubiquilin 4) Homo sapiens
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Symbol: UBQLN4
Name: ubiquilin 4
Description: Exhibits K48-linked polyubiquitin modification-dependent protein binding activity and identical protein binding activity. Involved in cellular response to DNA damage stimulus; negative regulation of double-strand break repair via homologous recombination; and regulation of cellular catabolic process. Localizes to several cellular components, including autophagosome; nucleoplasm; and site of DNA damage. Colocalizes with cytosolic proteasome complex and nuclear proteasome complex; PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A1U; A1Up; ataxin-1 interacting ubiquitin-like protein; ataxin-1 ubiquitin-like interacting protein; ataxin-1 ubiquitin-like-interacting protein A1U; C1orf6; CIP75; connexin43-interacting protein of 75 kDa; UBIN; ubiquilin-4
Orthologs:
Mus musculus (house mouse) : Ubqln4 (ubiquilin 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ubqln4 (ubiquilin 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ubqln4 (ubiquilin 4)
Pan paniscus (bonobo/pygmy chimpanzee) : UBQLN4 (ubiquilin 4)
Canis lupus familiaris (dog) : UBQLN4 (ubiquilin 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ubqln4 (ubiquilin 4)
Sus scrofa (pig) : UBQLN4 (ubiquilin 4)
Chlorocebus sabaeus (African green monkey) : UBQLN4 (ubiquilin 4)
Heterocephalus glaber (naked mole-rat) : Ubqln4 (ubiquilin 4)
more info ...
Related Pseudogenes: UBQLN4P1   UBQLN4P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1156,035,299 - 156,053,798 (-)EnsemblGRCh38hg38GRCh38
GRCh381156,033,129 - 156,053,798 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371156,002,945 - 156,023,613 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361154,271,716 - 154,290,140 (-)NCBINCBI36hg18NCBI36
Build 341152,818,165 - 152,836,589NCBI
Celera1129,078,055 - 129,096,477 (-)NCBI
Cytogenetic Map1q22NCBI
HuRef1127,367,831 - 127,386,064 (-)NCBIHuRef
CHM1_11157,401,165 - 157,419,703 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on UBQLN4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1344813
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.