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Gene: H2BC4 (H2B clustered histone 4) Homo sapiens
Symbol: H2BC4
Name: H2B clustered histone 4
Description: Exhibits identical protein binding activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide and defense response to other organism. Localizes to cytosol; extracellular space; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dJ221C16.3; H2B histone family, member L; H2B.1; H2B/a; H2B/g; H2B/h; H2B/k; H2B/l; H2BC10; H2BC6; H2BC7; H2BC8; H2BFL; HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI; histone 1, H2bc; histone cluster 1 H2B family member c; histone cluster 1, H2bc; histone H2B type 1-C/E/F/G/I; histone H2B.1 A; histone H2B.a; histone H2B.g; histone H2B.h; histone H2B.k; histone H2B.l; MGC104246
Mus musculus (house mouse) : H2bc4 (H2B clustered histone 4)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100989841 (histone H2B type 1-C/E/F/G/I)
Canis lupus familiaris (dog) : LOC478743 (histone H2B type 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl626,114,873 - 26,123,926 (-)EnsemblGRCh38hg38GRCh38
GRCh38626,113,170 - 26,123,926 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37626,113,389 - 26,124,266 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36626,231,674 - 26,232,111 (-)NCBINCBI36hg18NCBI36
Build 34626,231,673 - 26,232,111NCBI
Celera627,352,959 - 27,353,396 (-)NCBI
Cytogenetic Map6p22.2NCBI
HuRef626,066,734 - 26,067,171 (-)NCBIHuRef
CHM1_1626,125,932 - 26,126,369 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on H2BC4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1344863
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.