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Gene: CTAG2 (cancer/testis antigen 2) Homo sapiens
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Symbol: CTAG2
Name: cancer/testis antigen 2
Description: This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: autoimmunogenic cancer/testis antigen NY-ESO-2; CAMEL; cancer/testis antigen 6.2; cancer/testis antigen family 6, member 2a; cancer/testis antigen family 6, member 2b; CT2; CT6.2; CT6.2a; CT6.2b; CTL-recognized antigen on melanoma; ESO2; l antigen family member 1; LAGE-1; LAGE-1a protein; LAGE-2b; LAGE2B; MGC138724; MGC3803
Orthologs:
Mus musculus (house mouse) : Gm6890 (predicted gene 6890)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ctag2 (cancer/testis antigen 2)  Alliance
Canis lupus familiaris (dog) : LOC100683646 (EKC/KEOPS complex subunit LAGE3-like)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X154,651,972 - 154,653,579 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,880,246 - 153,881,853 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,533,445 - 153,535,036 (-)NCBINCBI36hg18NCBI36
Build 34X153,443,955 - 153,445,545NCBI
CeleraX154,038,327 - 154,039,934 (-)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,424,869 - 142,426,195 (-)NCBIHuRef
CHM1_1X153,791,956 - 153,793,563 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CTAG2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1344888
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.