Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PRB3 (proline rich protein BstNI subfamily 3) Homo sapiens
Symbol: PRB3
Name: proline rich protein BstNI subfamily 3
Description: This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. Multiple alleles of this gene exhibiting variations in the length of the tandem repeats have been identified. The reference genome encodes the "Long" allele. The protein isoforms encoded by this gene are recognized as the "first line of oral defense" against the detrimental effects of polyphenols in the diet and pathogen infections. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq, Nov 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: basic salivary proline-rich protein 3; BstNI type basic salivary proline-rich protein 3; G1; G1 parotid salivary glycoprotein; MGC116862; MGC116863; MGC116864; parotid salivary glycoprotein G1; PRG; proline-rich protein BstNI subfamily 3; proline-rich protein G1
No known orthologs. homologs ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1211,265,924 - 11,269,805 (-)EnsemblGRCh38hg38GRCh38
GRCh381211,265,914 - 11,269,707 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371211,418,847 - 11,422,656 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361211,310,124 - 11,313,908 (-)NCBINCBI36hg18NCBI36
Build 341211,310,124 - 11,313,908NCBI
Celera1216,561,234 - 16,564,894 (-)NCBI
Cytogenetic Map12p13.2NCBI
HuRef1211,182,948 - 11,186,545 (-)NCBIHuRef
CHM1_11211,384,083 - 11,387,753 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PRB3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345078
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.