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Gene: PIN4 (peptidylprolyl cis/trans isomerase, NIMA-interacting 4) Homo sapiens
Symbol: PIN4
Name: peptidylprolyl cis/trans isomerase, NIMA-interacting 4
Description: This gene encodes a member of the parvulin subfamily of the peptidyl-prolyl cis/trans isomerase protein family. The encoded protein catalyzes the isomerization of peptidylprolyl bonds, and may play a role in the cell cycle, chromatin remodeling, and/or ribosome biogenesis. The encoded protein may play an additional role in the mitochondria. [provided by RefSeq, Dec 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EPVH; eukaryotic parvulin homolog; hEPVH; hPar14; hPar17; MGC138486; PAR14; PAR17; parvulin; parvulin-14; parvulin-17; peptidyl-prolyl cis-trans isomerase NIMA-interacting 4; peptidyl-prolyl cis-trans isomerase Pin4; peptidyl-prolyl cis/trans isomerase EPVH; peptidylprolyl cis/trans isomerase NIMA-interacting, 4; PPIase PIN4; protein (peptidyl-prolyl cis/trans isomerase) nima-interacting, 4 (parvulin); rotamase PIN4
Related Pseudogenes: PIN4P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X72,181,676 - 72,263,964 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X71,401,526 - 71,483,814 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X71,318,251 - 71,334,666 (+)NCBINCBI36hg18NCBI36
Build 34X71,184,546 - 71,200,961NCBI
CeleraX71,749,520 - 71,827,026 (+)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX65,156,426 - 65,238,895 (+)NCBIHuRef
CHM1_1X71,294,590 - 71,376,836 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PIN4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345088
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.