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Gene: ENOX2 (ecto-NOX disulfide-thiol exchanger 2) Homo sapiens
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Symbol: ENOX2
Name: ecto-NOX disulfide-thiol exchanger 2
Description: This gene is a tumor-specific member of the ECTO-NOX family of genes that encode cell surface NADH oxidases. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The protein also displays prion-like properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APK1; APK1 antigen; COVA1; cytosolic ovarian carcinoma antigen 1; ecto-NADPH oxidase disulfide-thiol exchanger 2; tNOX; tumor-associated hydroquinone oxidase; tumor-associated NADH oxidase
Orthologs:
Mus musculus (house mouse) : Enox2 (ecto-NOX disulfide-thiol exchanger 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Enox2 (ecto-NOX disulfide-thiol exchanger 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Enox2 (ecto-NOX disulfide-thiol exchanger 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ENOX2 (ecto-NOX disulfide-thiol exchanger 2)
Canis lupus familiaris (dog) : ENOX2 (ecto-NOX disulfide-thiol exchanger 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Enox2 (ecto-NOX disulfide-thiol exchanger 2)
Sus scrofa (pig) : ENOX2 (ecto-NOX disulfide-thiol exchanger 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X130,622,330 - 130,903,317 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X129,757,355 - 130,037,219 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X129,585,036 - 129,864,889 (-)NCBINCBI36hg18NCBI36
Build 34X129,482,893 - 129,762,743NCBI
CeleraX130,143,767 - 130,423,625 (-)NCBI
Cytogenetic MapXq26.1NCBI
HuRefX119,152,711 - 119,430,022 (-)NCBIHuRef
CHM1_1X129,669,026 - 129,948,992 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ENOX2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345108
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.