Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: DEFA3 (defensin alpha 3) Homo sapiens
Analyze
Symbol: DEFA3
Name: defensin alpha 3
Description: Exhibits protein homodimerization activity. Involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; defense response to other organism; and intracellular estrogen receptor signaling pathway. Localizes to extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DEF3; defensin 3, neutrophil-specific; defensin, alpha 3; defensin, alpha 3, neutrophil-specific; HNP-3; HNP3; HP-3; HP3; neutrophil defensin 3; neutrophil peptide 3
Orthologs:
Mus musculus (house mouse) : Defa3 (defensin, alpha, 3)  MGI  Alliance
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl87,015,869 - 7,018,297 (-)EnsemblGRCh38hg38GRCh38
GRCh3887,015,869 - 7,018,336 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3786,873,391 - 6,875,816 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3686,860,805 - 6,863,226 (-)NCBINCBI36hg18NCBI36
Build 3486,860,804 - 6,863,226NCBI
Cytogenetic Map8p23.1NCBI
HuRef86,614,645 - 6,617,074 (-)NCBIHuRef
CHM1_186,961,928 - 6,964,357 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DEFA3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345125
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.