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Gene: MLLT1 (MLLT1 super elongation complex subunit) Homo sapiens
Symbol: MLLT1
Name: MLLT1 super elongation complex subunit
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN negative regulation of protein kinase activity (inferred); regulation of transcription by RNA polymerase II (inferred); transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCIATED WITH Abnormal Cortical Gyration; Developmental Disabilities; Hypertelorism; FOUND IN cytosol; fibrillar center; nucleoplasm; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-hydroxypropanoic acid; aflatoxin B1
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CTC-503J8.6; ENL; ENL/MLL fusion; LTG19; MLLT1, super elongation complex subunit; MLLT1/MLL fusion; myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog), translocated to, 1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1; YEATS domain-containing protein 1; YEATS1
Mus musculus (house mouse) : Mllt1 (myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mllt1 (MLLT1, super elongation complex subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mllt1 (MLLT1 super elongation complex subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : MLLT1 (MLLT1 super elongation complex subunit)
Canis lupus familiaris (dog) : MLLT1 (MLLT1 super elongation complex subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mllt1 (MLLT1 super elongation complex subunit)
Sus scrofa (pig) : MLLT1 (MLLT1 super elongation complex subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38196,210,381 - 6,279,975 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37196,210,392 - 6,279,959 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36196,161,392 - 6,230,959 (-)NCBINCBI36hg18NCBI36
Build 34196,163,965 - 6,230,959NCBI
Celera196,149,173 - 6,218,734 (-)NCBI
Cytogenetic Map19p13.3NCBI
HuRef195,969,364 - 6,038,974 (-)NCBIHuRef
CHM1_1196,209,972 - 6,279,567 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MLLT1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345161
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.