Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: MLLT1 (MLLT1 super elongation complex subunit) Homo sapiens
Analyze
Symbol: MLLT1
Name: MLLT1 super elongation complex subunit
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN negative regulation of protein kinase activity (inferred); regulation of transcription by RNA polymerase II (inferred); transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCIATED WITH Abnormal Cortical Gyration; Developmental Disabilities; Hypertelorism; FOUND IN cytosol; fibrillar center; nucleoplasm; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-hydroxypropanoic acid; aflatoxin B1
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CTC-503J8.6; ENL; ENL/MLL fusion; LTG19; MLLT1, super elongation complex subunit; MLLT1/MLL fusion; myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog), translocated to, 1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1; YEATS domain-containing protein 1; YEATS1
Orthologs:
Mus musculus (house mouse) : Mllt1 (myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mllt1 (MLLT1, super elongation complex subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mllt1 (MLLT1 super elongation complex subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : MLLT1 (MLLT1 super elongation complex subunit)
Canis lupus familiaris (dog) : MLLT1 (MLLT1 super elongation complex subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mllt1 (MLLT1 super elongation complex subunit)
Sus scrofa (pig) : MLLT1 (MLLT1 super elongation complex subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38196,210,381 - 6,279,975 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37196,210,392 - 6,279,959 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36196,161,392 - 6,230,959 (-)NCBINCBI36hg18NCBI36
Build 34196,163,965 - 6,230,959NCBI
Celera196,149,173 - 6,218,734 (-)NCBI
Cytogenetic Map19p13.3NCBI
HuRef195,969,364 - 6,038,974 (-)NCBIHuRef
CHM1_1196,209,972 - 6,279,567 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MLLT1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345161
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.