Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ITIH2 (inter-alpha-trypsin inhibitor heavy chain 2) Homo sapiens
Symbol: ITIH2
Name: inter-alpha-trypsin inhibitor heavy chain 2
CRRD ID: 1345234
Description: Predicted to have endopeptidase inhibitor activity. Predicted to be involved in post-translational protein modification. Localizes to blood microparticle; collagen-containing extracellular matrix; and extracellular exosome.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: H2P; inter-alpha (globulin) inhibitor H2; inter-alpha (globulin) inhibitor, H2 polypeptide; inter-alpha-inhibitor heavy chain 2; inter-alpha-trypsin inhibitor complex component II; inter-alpha-trypsin inhibitor heavy chain H2; ITI heavy chain H2; ITI-HC2; serum-derived hyaluronan-associated protein; SHAP
Mus musculus (house mouse) : Itih2 (inter-alpha trypsin inhibitor, heavy chain 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Itih2 (inter-alpha-trypsin inhibitor heavy chain 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itih2 (inter-alpha-trypsin inhibitor heavy chain 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ITIH2 (inter-alpha-trypsin inhibitor heavy chain 2)
Canis lupus familiaris (dog) : ITIH2 (inter-alpha-trypsin inhibitor heavy chain 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itih2 (inter-alpha-trypsin inhibitor heavy chain 2)
Sus scrofa (pig) : ITIH2 (inter-alpha-trypsin inhibitor heavy chain 2)
Chlorocebus sabaeus (African green monkey) : ITIH2 (inter-alpha-trypsin inhibitor heavy chain 2)
Heterocephalus glaber (naked mole-rat) : Itih2 (inter-alpha-trypsin inhibitor heavy chain 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl107,703,316 - 7,749,520 (+)EnsemblGRCh38hg38GRCh38
GRCh38107,703,316 - 7,749,520 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37107,745,236 - 7,791,483 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36107,785,242 - 7,831,489 (+)NCBINCBI36hg18NCBI36
Build 34107,785,342 - 7,831,488NCBI
Celera107,671,050 - 7,717,293 (+)NCBI
Cytogenetic Map10p14NCBI
HuRef107,663,584 - 7,709,831 (+)NCBIHuRef
CHM1_1107,745,665 - 7,791,444 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ITIH2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345234
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.