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Gene: SNX3 (sorting nexin 3) Homo sapiens
Symbol: SNX3
Name: sorting nexin 3
Description: Exhibits phosphatidylinositol-3-phosphate binding activity and protein phosphatase binding activity. Involved in several processes, including intralumenal vesicle formation; negative regulation of transport; and negative regulation of viral entry into host cell. Localizes to the cytoplasmic vesicle and cytosol. Colocalizes with the retromer complex. Implicated in microphthalmia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Grd19; MCOPS8; MGC17570; SDP3; sorting nexin 3A; sorting nexin-3
Mus musculus (house mouse) : Snx3 (sorting nexin 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Snx3 (sorting nexin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snx3 (sorting nexin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SNX3 (sorting nexin 3)
Canis lupus familiaris (dog) : SNX3 (sorting nexin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snx3 (sorting nexin 3)
Sus scrofa (pig) : SNX3 (sorting nexin 3)
more info ...
Related Pseudogenes: SNX3P1X   SNX3P1Y  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl6108,211,222 - 108,261,246 (-)Ensembl
GRCh386108,211,222 - 108,261,040 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376108,532,712 - 108,582,478 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366108,639,410 - 108,689,156 (-)NCBINCBI36hg18NCBI36
Build 346108,639,410 - 108,689,156NCBI
Celera6109,279,209 - 109,328,955 (-)NCBI
Cytogenetic Map6q21NCBI
HuRef6106,100,989 - 106,150,564 (-)NCBIHuRef
CHM1_16108,795,378 - 108,845,435 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SNX3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345268
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.