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Gene: AKAP5 (A-kinase anchoring protein 5) Homo sapiens
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Symbol: AKAP5
Name: A-kinase anchoring protein 5
Description: Exhibits several functions, including SH3 domain binding activity; enzyme binding activity; and protein kinase A regulatory subunit binding activity. Involved in several processes, including negative regulation of adenylate cyclase activity; positive regulation of protein localization to plasma membrane; and regulation of protein kinase A signaling. Localizes to the cytoplasmic side of plasma membrane and membrane raft. Biomarker of Alzheimer's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A kinase (PRKA) anchor protein 5; A-kinase anchor protein 5; A-kinase anchor protein 79 kDa; A-kinase anchor protein, 79kDa; A-kinase anchoring protein 75/79; AKAP 79; AKAP-5; AKAP75; AKAP79; cAMP-dependent protein kinase regulatory subunit II high affinity binding protein; cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein; H21
Orthologs:
Mus musculus (house mouse) : Akap5 (A kinase (PRKA) anchor protein 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Akap5 (A-kinase anchoring protein 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akap5 (A-kinase anchoring protein 5)
Pan paniscus (bonobo/pygmy chimpanzee) : AKAP5 (A-kinase anchoring protein 5)
Canis lupus familiaris (dog) : AKAP5 (A-kinase anchoring protein 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akap5 (A-kinase anchoring protein 5)
Sus scrofa (pig) : AKAP5 (A-kinase anchoring protein 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381464,465,499 - 64,474,503 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371464,932,217 - 64,941,221 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361464,001,970 - 64,010,974 (+)NCBINCBI36hg18NCBI36
Build 341464,003,577 - 64,006,172NCBI
Celera1444,989,946 - 44,998,950 (+)NCBI
Cytogenetic Map14q23.3ENTREZGENE
HuRef1445,104,846 - 45,113,850 (+)NCBIHuRef
CHM1_11464,871,930 - 64,880,934 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on AKAP5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345297
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-22
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.