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Gene: SRGAP3 (SLIT-ROBO Rho GTPase activating protein 3) Homo sapiens
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Symbol: SRGAP3
Name: SLIT-ROBO Rho GTPase activating protein 3
Description: Predicted to have Rac GTPase binding activity. Predicted to be involved in negative regulation of cell migration. Predicted to localize to the cytoplasm; INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ARHGAP14; KIAA0411; MEGAP; mental disorder-associated GAP; rho GTPase-activating protein 14; SLIT-ROBO Rho GTPase activating protein 2; SLIT-ROBO Rho GTPase-activating protein 3; SRGAP2; WAVE-associated Rac GTPase activating protein; WAVE-associated Rac GTPase-activating protein; WRP
Orthologs:
Mus musculus (house mouse) : Srgap3 (SLIT-ROBO Rho GTPase activating protein 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Srgap3 (SLIT-ROBO Rho GTPase activating protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srgap3 (SLIT-ROBO Rho GTPase activating protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SRGAP3 (SLIT-ROBO Rho GTPase activating protein 3)
Canis lupus familiaris (dog) : SRGAP3 (SLIT-ROBO Rho GTPase activating protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srgap3 (SLIT-ROBO Rho GTPase activating protein 3)
Sus scrofa (pig) : SRGAP3 (SLIT-ROBO Rho GTPase activating protein 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl38,980,591 - 9,363,053 (-)Ensembl
GRCh3838,980,591 - 9,363,446 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3739,022,275 - 9,291,369 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3638,997,278 - 9,266,311 (-)NCBINCBI36hg18NCBI36
Build 3438,997,277 - 9,265,737NCBI
Celera38,956,988 - 9,226,019 (-)NCBI
Cytogenetic Map3p25.3NCBI
HuRef38,956,444 - 9,225,356 (-)NCBIHuRef
CHM1_138,972,526 - 9,241,578 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on SRGAP3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345309
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.