Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ERAS (ES cell expressed Ras) Homo sapiens
Analyze
Symbol: ERAS
Name: ES cell expressed Ras
Description: This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E-Ras; embryonic stem cell-expressed Ras; GTPase ERas; HRAS2; HRASP; MGC126691; MGC126693; small GTPase protein E-Ras; v-Ha-ras Harvey rat sarcoma viral oncogene homolog 2; v-Ha-ras Harvey rat sarcoma viral oncogene homolog pseudogene
Orthologs:
Mus musculus (house mouse) : Eras (ES cell-expressed Ras)  MGI  Alliance
Rattus norvegicus (Norway rat) : Eras (ES cell expressed Ras)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eras (ES cell expressed Ras)
Pan paniscus (bonobo/pygmy chimpanzee) : ERAS (ES cell expressed Ras)
Canis lupus familiaris (dog) : ERAS (ES cell expressed Ras)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Eras (ES cell expressed Ras)
Sus scrofa (pig) : ERAS (ES cell expressed Ras)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X48,826,513 - 48,829,869 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X48,684,923 - 48,688,279 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,572,227 - 48,573,492 (+)NCBINCBI36hg18NCBI36
Build 34X48,443,531 - 48,444,797NCBI
CeleraX52,974,981 - 52,976,246 (-)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX46,344,561 - 46,347,994 (+)NCBIHuRef
CHM1_1X48,716,067 - 48,719,421 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
 
More on ERAS
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345319
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.