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Gene: PSG6 (pregnancy specific beta-1-glycoprotein 6) Homo sapiens
Symbol: PSG6
Name: pregnancy specific beta-1-glycoprotein 6
Description: This gene is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The protein encoded by this gene contains the Arg-Gly-Asp tripeptide associated with cellular adhesion and recognition. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: pregnancy-specific beta-1-glycoprotein 10; pregnancy-specific beta-1-glycoprotein 12; pregnancy-specific beta-1-glycoprotein 6; pregnancy-specific glycoprotein 10; pregnancy-specific glycoprotein 12; pregnancy-specific glycoprotein 6; PS-beta-G-10; PS-beta-G-12; PS-beta-G-6; PSBG-10; PSBG-12; PSBG-6; PSG10; PSGGB
No known orthologs. homologs ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1942,902,079 - 42,919,563 (-)EnsemblGRCh38hg38GRCh38
GRCh381942,902,086 - 42,917,894 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371943,406,234 - 43,422,076 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361948,098,080 - 48,113,883 (-)NCBINCBI36hg18NCBI36
Build 341948,099,607 - 48,113,829NCBI
Celera1940,206,738 - 40,222,541 (-)NCBI
Cytogenetic Map19q13.31NCBI
HuRef1939,835,912 - 39,851,754 (-)NCBIHuRef
CHM1_11943,407,893 - 43,423,735 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PSG6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345325
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.