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Gene: GSTO1 (glutathione S-transferase omega 1) Homo sapiens
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Symbol: GSTO1
Name: glutathione S-transferase omega 1
Description: Exhibits glutathione dehydrogenase (ascorbate) activity and glutathione transferase activity. Involved in several processes, including L-ascorbic acid metabolic process; cellular response to arsenic-containing substance; and regulation of release of sequestered calcium ion into cytosol. Localizes to cytosol and nucleoplasm. Implicated in Alzheimer's disease and Parkinson's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686H13163; epididymis secretory protein Li 21; glutathione S-transferase omega 1-1; glutathione S-transferase omega-1; glutathione transferase omega 1; glutathione-dependent dehydroascorbate reductase; glutathione-S-transferase like; GSTO 1-1; GSTO-1; GSTTLp28; HEL-S-21; MMA(V) reductase; monomethylarsonic acid reductase; P28; S-(Phenacyl)glutathione reductase; SPG-R
Orthologs:
Mus musculus (house mouse) : Gsto1 (glutathione S-transferase omega 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gsto1 (glutathione S-transferase omega 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : GSTO1 (glutathione S-transferase omega 1)
Canis lupus familiaris (dog) : GSTO1 (glutathione S-transferase omega 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gsto1 (glutathione S-transferase omega 1)
Sus scrofa (pig) : GSTO1 (glutathione S-transferase omega 1)
Chlorocebus sabaeus (African green monkey) : GSTO1 (glutathione S-transferase omega 1)
Heterocephalus glaber (naked mole-rat) : Gsto1 (glutathione S-transferase omega 1)
more info ...
Related Pseudogenes: GSTO3P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl10104,235,356 - 104,267,459 (+)EnsemblGRCh38hg38GRCh38
GRCh3810104,254,194 - 104,267,464 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710106,013,952 - 106,027,222 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610106,004,668 - 106,017,203 (+)NCBINCBI36hg18NCBI36
Build 3410106,004,667 - 106,017,199NCBI
Celera1099,754,787 - 99,768,056 (+)NCBI
Cytogenetic Map10q25.1NCBI
HuRef1099,645,735 - 99,659,002 (+)NCBIHuRef
CHM1_110106,297,838 - 106,311,108 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
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miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on GSTO1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345331
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.