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Gene: SPCS2 (signal peptidase complex subunit 2) Homo sapiens
Symbol: SPCS2
Name: signal peptidase complex subunit 2
CRRD ID: 1345346
Description: Predicted to have peptidase activity. Predicted to be involved in protein targeting to ER and signal peptide processing. Predicted to localize to signal peptidase complex; INTERACTS WITH 17beta-hydroxy-5alpha-androstan-3-one; 2-hydroxypropanoic acid; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KIAA0102; MGC117366; microsomal signal peptidase 25 kDa subunit; signal peptidase 25kDa subunit; signal peptidase complex subunit 2 homolog; SPase 25 kDa subunit
Mus musculus (house mouse) : Spcs2 (signal peptidase complex subunit 2 homolog (S. cerevisiae))  MGI  Alliance
Rattus norvegicus (Norway rat) : Spcs2 (signal peptidase complex subunit 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spcs2 (signal peptidase complex subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SPCS2 (signal peptidase complex subunit 2)
Canis lupus familiaris (dog) : SPCS2 (signal peptidase complex subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spcs2 (signal peptidase complex subunit 2)
Sus scrofa (pig) : SPCS2 (signal peptidase complex subunit 2)
Chlorocebus sabaeus (African green monkey) : SPCS2 (signal peptidase complex subunit 2)
Heterocephalus glaber (naked mole-rat) : Spcs2 (signal peptidase complex subunit 2)
more info ...
Related Pseudogenes: SPCS2P1   SPCS2P2   SPCS2P3   SPCS2P4  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1174,949,247 - 74,979,033 (+)EnsemblGRCh38hg38GRCh38
GRCh381174,949,266 - 74,979,033 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371174,660,292 - 74,690,076 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361174,337,981 - 74,366,427 (+)NCBINCBI36hg18NCBI36
Build 341174,337,980 - 74,366,427NCBI
Celera1171,966,858 - 71,996,651 (+)NCBI
Cytogenetic Map11q13.4NCBI
HuRef1170,957,090 - 70,986,883 (+)NCBIHuRef
CHM1_11174,543,689 - 74,573,473 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SPCS2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345346
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.