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Gene: NUDT5 (nudix hydrolase 5) Homo sapiens
Symbol: NUDT5
Name: nudix hydrolase 5
CRRD ID: 1345366
Description: Exhibits several functions, including magnesium ion binding activity; protein homodimerization activity; and pyrophosphatase activity. Involved in several processes, including ATP generation from poly-ADP-D-ribose; D-ribose catabolic process; and ribonucleoside diphosphate catabolic process. Localizes to nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 8-oxo-dGDP phosphatase; ADP-sugar pyrophosphatase; hNUDT5; hYSAH1; nuclear ATP-synthesis protein NUDIX5; nucleoside diphosphate linked moiety X-type motif 5; nucleoside diphosphate-linked moiety X motif 5; nudix (nucleoside diphosphate linked moiety X)-type motif 5; nudix motif 5; YSA1; YSA1H; YSAH1
Mus musculus (house mouse) : Nudt5 (nudix (nucleoside diphosphate linked moiety X)-type motif 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nudt5 (nudix hydrolase 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nudt5 (nudix hydrolase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : NUDT5 (nudix hydrolase 5)
Canis lupus familiaris (dog) : NUDT5 (nudix hydrolase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nudt5 (nudix hydrolase 5)
Sus scrofa (pig) : NUDT5 (nudix hydrolase 5)
Chlorocebus sabaeus (African green monkey) : NUDT5 (nudix hydrolase 5)
Heterocephalus glaber (naked mole-rat) : Nudt5 (nudix hydrolase 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1012,165,330 - 12,196,144 (-)EnsemblGRCh38hg38GRCh38
GRCh381012,165,330 - 12,195,891 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371012,209,573 - 12,238,143 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361012,249,579 - 12,278,149 (-)NCBINCBI36hg18NCBI36
Build 341012,249,579 - 12,278,149NCBI
Celera1012,139,104 - 12,167,676 (-)NCBI
Cytogenetic Map10p14NCBI
HuRef1012,126,113 - 12,154,585 (-)NCBIHuRef
CHM1_11012,207,322 - 12,238,155 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NUDT5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345366
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.