Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: RSPO3 (R-spondin 3) Homo sapiens
Symbol: RSPO3
Name: R-spondin 3
Description: Exhibits signaling receptor binding activity. Involved in positive regulation of Wnt signaling pathway. Predicted to localize to extracellular region.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CRISTIN1; FLJ14440; hPWTSR; hRspo3; protein with TSP type-1 repeat; PWTSR; R-spondin 3 homolog; R-spondin-3; roof plate-specific spondin-3; thrombospondin type-1 domain-containing protein 2; thrombospondin, type I, domain containing 2; thrombospondin-like; THSD2
Mus musculus (house mouse) : Rspo3 (R-spondin 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rspo3 (R-spondin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rspo3 (R-spondin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : RSPO3 (R-spondin 3)
Canis lupus familiaris (dog) : RSPO3 (R-spondin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rspo3 (R-spondin 3)
Sus scrofa (pig) : RSPO3 (R-spondin 3)
Chlorocebus sabaeus (African green monkey) : RSPO3 (R-spondin 3)
Heterocephalus glaber (naked mole-rat) : Rspo3 (R-spondin 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl6127,118,671 - 127,199,481 (+)EnsemblGRCh38hg38GRCh38
GRCh386127,118,671 - 127,199,481 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376127,439,844 - 127,520,626 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366127,481,741 - 127,559,877 (+)NCBINCBI36hg18NCBI36
Build 346127,481,748 - 127,559,877NCBI
Celera6128,182,296 - 128,260,461 (+)NCBI
Cytogenetic Map6q22.33NCBI
HuRef6125,016,583 - 125,097,147 (+)NCBIHuRef
CHM1_16127,704,346 - 127,784,940 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RSPO3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345376
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.