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Gene: ETV6 (ETS variant transcription factor 6) Homo sapiens
Symbol: ETV6
Name: ETS variant transcription factor 6
CRRD ID: 1345405
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and protein domain specific binding activity. Involved in hematopoietic stem cell proliferation and negative regulation of transcription by RNA polymerase II. Localizes to cytosol and nucleolus. Implicated in hematologic cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ETS translocation variant 6; ETS variant 6; ets variant gene 6 (TEL oncogene); ETS-related protein Tel1; malignant proliferation, eosinophil; MPE; TEL; TEL/ABL; TEL1 oncogene; THC5; transcription factor ETV6
Mus musculus (house mouse) : Etv6 (ets variant 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Etv6 (ETS variant transcription factor 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Etv6 (ETS variant transcription factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ETV6 (ETS variant transcription factor 6)
Canis lupus familiaris (dog) : ETV6 (ETS variant transcription factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Etv6 (ETS variant transcription factor 6)
Sus scrofa (pig) : ETV6 (ETS variant transcription factor 6)
Chlorocebus sabaeus (African green monkey) : ETV6 (ETS variant transcription factor 6)
Heterocephalus glaber (naked mole-rat) : Etv6 (ETS variant transcription factor 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1211,649,674 - 11,895,377 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1211,649,854 - 11,895,402 (+)EnsemblGRCh38hg38GRCh38
GRCh381211,649,601 - 11,895,386 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371211,802,788 - 12,048,336 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361211,694,055 - 11,939,603 (+)NCBINCBI36hg18NCBI36
Build 341211,694,054 - 11,939,590NCBI
Celera1216,945,067 - 17,191,403 (+)NCBI
Cytogenetic Map12p13.2NCBI
HuRef1211,670,991 - 11,813,778 (+)NCBIHuRef
CHM1_11211,768,106 - 12,013,345 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ETV6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345405
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-11-03
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.