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Gene: GIT2 (GIT ArfGAP 2) Homo sapiens
Symbol: GIT2
Name: GIT ArfGAP 2
CRRD ID: 1345420
Description: Predicted to have GTPase activator activity and metal ion binding activity. Predicted to be involved in behavioral response to pain; presynaptic modulation of chemical synaptic transmission; and regulation of synaptic vesicle exocytosis. Localizes to nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ARF GAP GIT2; ARF GTPase-activating protein GIT2; CAT-2; CAT2; cool-associated, tyrosine phosphorylated protein 2; cool-interacting tyrosine-phosphorylated protein 2; DKFZp686G01261; G protein-coupled receptor kinase interacting ArfGAP 2; G protein-coupled receptor kinase interactor 2; G protein-coupled receptor kinase-interactor 2; GRK-interacting protein 2; KIAA0148; MGC760; Paxillin kinase linker; PKL
Mus musculus (house mouse) : Git2 (GIT ArfGAP 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Git2 (GIT ArfGAP 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Git2 (GIT ArfGAP 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GIT2 (GIT ArfGAP 2)
Canis lupus familiaris (dog) : GIT2 (GIT ArfGAP 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Git2 (GIT ArfGAP 2)
Sus scrofa (pig) : GIT2 (GIT ArfGAP 2)
Chlorocebus sabaeus (African green monkey) : GIT2 (GIT ArfGAP 2)
Heterocephalus glaber (naked mole-rat) : Git2 (GIT ArfGAP 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl12109,929,802 - 109,996,389 (-)EnsemblGRCh38hg38GRCh38
GRCh3812109,929,792 - 109,996,368 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712110,367,607 - 110,434,194 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612108,851,992 - 108,918,483 (-)NCBINCBI36hg18NCBI36
Build 3412108,848,588 - 108,896,820NCBI
Celera12109,991,955 - 110,058,428 (-)NCBI
Cytogenetic Map12q24.11NCBI
HuRef12107,383,692 - 107,449,937 (-)NCBIHuRef
CHM1_112110,335,391 - 110,401,989 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GIT2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345420
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.