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Gene: KCNK3 (potassium two pore domain channel subfamily K member 3) Homo sapiens
Symbol: KCNK3
Name: potassium two pore domain channel subfamily K member 3
CRRD ID: 1345497
Description: Exhibits S100 protein binding activity and potassium ion leak channel activity. Involved in ion transmembrane transport. Localizes to plasma membrane. Implicated in primary pulmonary hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: acid-sensitive potassium channel protein TASK; acid-sensitive potassium channel protein TASK-1; cardiac potassium channel; K2p3.1; OAT1; potassium channel subfamily K member 3; potassium channel, two pore domain subfamily K, member 3; potassium inwardly-rectifying channel, subfamily K, member 3; PPH4; TASK; TASK-1; TASK1; TBAK1; TWIK-related acid-sensitive K(+) channel 1; TWIK-related acid-sensitive K+ 1; TWIK-related acid-sensitive K+ channel; two P domain potassium channel; two pore K(+) channel KT3.1; two pore potassium channel KT3.1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl226,692,690 - 26,733,420 (+)EnsemblGRCh38hg38GRCh38
GRCh38226,692,722 - 26,733,420 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37226,915,581 - 26,954,066 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36226,769,123 - 26,806,222 (+)NCBINCBI36hg18NCBI36
Build 34226,827,269 - 26,864,354NCBI
Celera226,759,188 - 26,800,097 (+)NCBI
Cytogenetic Map2p23.3NCBI
HuRef226,654,995 - 26,695,894 (+)NCBIHuRef
CHM1_1226,845,436 - 26,883,789 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KCNK3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345497
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.