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Gene: TXNDC8 (thioredoxin domain containing 8) Homo sapiens
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Symbol: TXNDC8
Name: thioredoxin domain containing 8
Description: Involved in spermatogenesis. Localizes to the Golgi apparatus. Biomarker of male infertility; INTERACTS WITH aflatoxin B1; benzo[a]pyrene (ortholog); bisphenol A (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bA427L11.2; sperm-specific thioredoxin 3; spermatid-specific thioredoxin-3; spermatocyte/spermatid-specific thioredoxin-3; SPTRX-3; SPTRX3; thioredoxin 6; thioredoxin domain containing 8 (spermatozoa); thioredoxin domain-containing protein 8; thioredoxin-6; TRX6
Orthologs:
Mus musculus (house mouse) : Txndc8 (thioredoxin domain containing 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Txndc8 (thioredoxin domain containing 8)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : TXNDC8 (thioredoxin domain containing 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Txndc8 (thioredoxin domain containing 8)
Sus scrofa (pig) : TXNDC8 (thioredoxin domain containing 8 (spermatozoa))
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389110,300,900 - 110,337,887 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379113,065,762 - 113,100,163 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369112,105,688 - 112,139,909 (-)NCBINCBI36hg18NCBI36
Build 349110,145,423 - 110,179,643NCBI
Celera983,567,488 - 83,601,762 (-)NCBI
Cytogenetic Map9q31.3NCBI
HuRef982,667,542 - 82,701,767 (-)NCBIHuRef
CHM1_19113,212,292 - 113,246,585 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TXNDC8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345541
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.