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Gene: F7 (coagulation factor VII) Homo sapiens
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Symbol: F7
Name: coagulation factor VII
Description: Contributes to serine-type endopeptidase activity. Involved in several processes, including blood coagulation; positive regulation of chemotaxis; and positive regulation of signal transduction. Localizes to the serine-type peptidase complex. Implicated in several diseases, including acute pancreatitis; artery disease (multiple); diabetes mellitus (multiple); inherited blood coagulation disease (multiple); and obesity. Biomarker of several diseases, including artery disease (multiple); diabetic neuropathy; glucose metabolism disease (multiple); hereditary angioedema; and kidney disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; FVII coagulation protein; FVIIa; proconvertin; serum prothrombin conversion accelerator; SPCA
Orthologs:
Mus musculus (house mouse) : F7 (coagulation factor VII)  MGI  Alliance
Rattus norvegicus (Norway rat) : F7 (coagulation factor VII)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F7 (coagulation factor VII)
Pan paniscus (bonobo/pygmy chimpanzee) : F7 (coagulation factor VII)
Canis lupus familiaris (dog) : F7 (coagulation factor VII)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F7 (coagulation factor VII)
Sus scrofa (pig) : F7 (coagulation factor VII)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl13113,105,788 - 113,120,681 (+)Ensembl
GRCh3813113,105,773 - 113,120,685 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3713113,760,102 - 113,774,995 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3613112,808,106 - 112,822,996 (+)NCBINCBI36hg18NCBI36
Build 3413112,808,105 - 112,822,346NCBI
Celera1394,585,687 - 94,600,980 (+)NCBI
Cytogenetic Map13q34NCBI
HuRef1394,198,534 - 94,213,700 (+)NCBIHuRef
CHM1_113113,728,824 - 113,743,117 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on F7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345586
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.