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Gene: NFIL3 (nuclear factor, interleukin 3 regulated) Homo sapiens
Symbol: NFIL3
Name: nuclear factor, interleukin 3 regulated
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E4 promoter-binding protein 4; E4BP4; IL3BP1; interleukin-3 promoter transcriptional activator; interleukin-3-binding protein 1; NF-IL3A; NFIL3A; nuclear factor interleukin 3 regulated protein; nuclear factor interleukin-3-regulated protein; transcriptional activator NF-IL3A
Mus musculus (house mouse) : Nfil3 (nuclear factor, interleukin 3, regulated)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nfil3 (nuclear factor, interleukin 3 regulated)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfil3 (nuclear factor, interleukin 3 regulated)
Pan paniscus (bonobo/pygmy chimpanzee) : NFIL3 (nuclear factor, interleukin 3 regulated)
Canis lupus familiaris (dog) : NFIL3 (nuclear factor, interleukin 3 regulated)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfil3 (nuclear factor, interleukin 3 regulated)
Sus scrofa (pig) : NFIL3 (nuclear factor, interleukin 3 regulated)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38991,409,045 - 91,425,063 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37994,171,327 - 94,186,908 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36993,211,148 - 93,225,965 (-)NCBINCBI36hg18NCBI36
Build 34991,250,883 - 91,265,699NCBI
Celera964,605,969 - 64,620,785 (-)NCBI
Cytogenetic Map9q22.31NCBI
HuRef963,851,695 - 63,866,454 (-)NCBIHuRef
CHM1_1994,317,789 - 94,333,349 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NFIL3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345604
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.