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Gene: SFRP2 (secreted frizzled related protein 2) Homo sapiens
Symbol: SFRP2
Name: secreted frizzled related protein 2
Description: Predicted to have Wnt-protein binding activity; fibronectin binding activity; and signaling receptor binding activity. Involved in several processes, including heart morphogenesis; negative regulation of epithelial to mesenchymal transition; and positive regulation of fat cell differentiation. Localizes to the extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FRP-2; SARP-1; SARP1; SDF-5; secreted apoptosis related protein 1; secreted apoptosis-related protein 1; secreted frizzled-related protein 2; sFRP-2; testicular tissue protein Li 170
Mus musculus (house mouse) : Sfrp2 (secreted frizzled-related protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sfrp2 (secreted frizzled-related protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sfrp2 (secreted frizzled related protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SFRP2 (secreted frizzled related protein 2)
Canis lupus familiaris (dog) : SFRP2 (secreted frizzled related protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sfrp2 (secreted frizzled related protein 2)
Sus scrofa (pig) : SFRP2 (secreted frizzled related protein 2)
Chlorocebus sabaeus (African green monkey) : SFRP2 (secreted frizzled related protein 2)
Heterocephalus glaber (naked mole-rat) : Sfrp2 (secreted frizzled related protein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl4153,780,591 - 153,789,083 (-)EnsemblGRCh38hg38GRCh38
GRCh384153,780,591 - 153,789,083 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374154,701,742 - 154,710,228 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364154,921,192 - 154,929,678 (-)NCBINCBI36hg18NCBI36
Build 344155,059,346 - 155,067,833NCBI
Celera4152,026,238 - 152,034,728 (-)NCBI
Cytogenetic Map4q31.3NCBI
HuRef4150,432,908 - 150,441,398 (-)NCBIHuRef
CHM1_14154,680,045 - 154,688,529 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SFRP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345643
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.