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Gene: IKZF1 (IKAROS family zinc finger 1) Homo sapiens
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Symbol: IKZF1
Name: IKAROS family zinc finger 1
Description: Exhibits DNA binding activity and protein domain specific binding activity. Involved in erythrocyte differentiation; lymphocyte differentiation; and protein heterooligomerization. Localizes to the nuclear pericentric heterochromatin and protein-containing complex. Implicated in common variable immunodeficiency and precursor B lymphoblastic lymphoma/leukemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CLL-associated antigen KW-6; CVID13; DNA-binding protein Ikaros; hIk-1; Hs.54452; IK1; IKAROS; Ikaros (zinc finger protein); IKAROS family zinc finger 1 (Ikaros); ikaros family zinc finger protein 1; LyF-1; LYF1; lymphoid transcription factor LyF-1; PPP1R92; PRO0758; zinc finger protein, subfamily 1A, 1 (Ikaros); ZNFN1A1
Orthologs:
Mus musculus (house mouse) : Ikzf1 (IKAROS family zinc finger 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ikzf1 (IKAROS family zinc finger 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ikzf1 (IKAROS family zinc finger 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IKZF1 (IKAROS family zinc finger 1)
Canis lupus familiaris (dog) : IKZF1 (IKAROS family zinc finger 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ikzf1 (IKAROS family zinc finger 1)
Sus scrofa (pig) : IKZF1 (IKAROS family zinc finger 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38750,303,453 - 50,405,101 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37750,344,378 - 50,367,358 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh37750,444,231 - 50,472,799 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36750,411,725 - 50,440,293 (+)NCBINCBI36hg18NCBI36
Build 34750,218,438 - 50,244,768NCBI
Celera750,439,276 - 50,537,765 (+)NCBI
Cytogenetic Map7p12.2NCBI
HuRef750,294,198 - 50,322,765 (+)NCBIHuRef
HuRef750,224,730 - 50,247,709 (+)NCBIHuRef
CHM1_1750,345,970 - 50,475,092 (+)NCBICHM1_1
CRA_TCAGchr7v2750,381,631 - 50,478,870 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IKZF1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345718
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.