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Gene: SF3B5 (splicing factor 3b subunit 5) Homo sapiens
Symbol: SF3B5
Name: splicing factor 3b subunit 5
Description: Exhibits RNA binding activity and splicing factor binding activity. Involved in mRNA splicing, via spliceosome. Localizes to U12-type spliceosomal complex; U2-type precatalytic spliceosome; and nucleoplasm; PARTICIPATES IN spliceosome pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; bisphenol A; chloropicrin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC3133; pre-mRNA-splicing factor SF3b 10 kDa subunit; SF3b10; splicing factor 3b, subunit 5, 10kDa; Ysf3
Mus musculus (house mouse) : Sf3b5 (splicing factor 3b, subunit 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sf3b5 (splicing factor 3b, subunit 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sf3b5 (splicing factor 3b subunit 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SF3B5 (splicing factor 3b subunit 5)
Canis lupus familiaris (dog) : SF3B5 (splicing factor 3b subunit 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sf3b5 (splicing factor 3b subunit 5)
Sus scrofa (pig) : SF3B5 (splicing factor 3b subunit 5)
Chlorocebus sabaeus (African green monkey) : SF3B5 (splicing factor 3b subunit 5)
Heterocephalus glaber (naked mole-rat) : Sf3b5 (splicing factor 3b subunit 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl6144,094,884 - 144,095,573 (-)EnsemblGRCh38hg38GRCh38
GRCh386144,094,884 - 144,095,573 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376144,416,018 - 144,416,754 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366144,457,711 - 144,458,447 (-)NCBINCBI36hg18NCBI36
Build 346144,457,710 - 144,458,447NCBI
Celera6145,156,476 - 145,157,212 (-)NCBI
Cytogenetic Map6q24.2NCBI
HuRef6141,979,710 - 141,980,446 (-)NCBIHuRef
CHM1_16144,678,914 - 144,679,650 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SF3B5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345762
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.