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Gene: ARL6IP1 (ADP ribosylation factor like GTPase 6 interacting protein 1) Homo sapiens
Symbol: ARL6IP1
Name: ADP ribosylation factor like GTPase 6 interacting protein 1
Description: Exhibits identical protein binding activity. Involved in endoplasmic reticulum tubular network formation; endoplasmic reticulum tubular network membrane organization; and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process. Localizes to the integral component of endoplasmic reticulum membrane. Implicated in hereditary spastic paraplegia 61.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADP-ribosylation factor GTPase 6 interacting protein 1; ADP-ribosylation factor like GTPase 6 interacting protein 1; ADP-ribosylation factor-like 6 interacting protein 1; ADP-ribosylation factor-like protein 6-interacting protein 1; aip-1; AIP1; apoptotic regulator in the membrane of the endoplasmic reticulum; ARL-6-interacting protein 1; ARL6IP; ARMER; KIAA0069; SPG61
Related Pseudogenes: ARL6IP1P1   ARL6IP1P2   ARL6IP1P3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381618,791,667 - 18,801,549 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371618,802,991 - 18,812,894 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361618,710,492 - 18,720,358 (-)NCBINCBI36hg18NCBI36
Build 341618,710,491 - 18,720,358NCBI
Celera1617,956,727 - 17,966,592 (-)NCBI
Cytogenetic Map16p12.3NCBI
HuRef1617,345,174 - 17,355,038 (-)NCBIHuRef
CHM1_11618,890,470 - 18,900,481 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ARL6IP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345801
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.