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Gene: SSX3 (SSX family member 3) Homo sapiens
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Symbol: SSX3
Name: SSX family member 3
Description: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas, this gene does not appear to be involved in such translocations. [provided by RefSeq, Jul 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen 5.3; CT5.3; Kruppel-associated box containing gene product SSX3; MGC119054; MGC14495; synovial sarcoma, X breakpoint 3; synovial sarcoma, X breakpoint 3, isoform a
Orthologs:
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100995951 (protein SSX3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X48,346,427 - 48,356,706 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X48,205,863 - 48,216,203 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,090,807 - 48,101,086 (-)NCBINCBI36hg18NCBI36
Build 34X47,963,949 - 47,972,396NCBI
CeleraX52,402,209 - 52,412,488 (-)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX45,914,469 - 45,924,848 (-)NCBIHuRef
CHM1_1X48,237,472 - 48,247,797 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SSX3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345829
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.