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Gene: DUSP3 (dual specificity phosphatase 3) Homo sapiens
Symbol: DUSP3
Name: dual specificity phosphatase 3
CRRD ID: 1345861
Description: Exhibits cytoskeletal protein binding activity; phosphoprotein phosphatase activity; and receptor tyrosine kinase binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; negative regulation of MAPK cascade; and regulation of cell-substrate junction organization. Localizes to cytosol; immunological synapse; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dual specificity protein phosphatase 3; dual specificity protein phosphatase VHR; serine/threonine specific protein phosphatase; vaccinia H1-related phosphatase; vaccinia virus phosphatase VH1-related; VHR
Mus musculus (house mouse) : Dusp3 (dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related))  MGI  Alliance
Rattus norvegicus (Norway rat) : Dusp3 (dual specificity phosphatase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dusp3 (dual specificity phosphatase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : DUSP3 (dual specificity phosphatase 3)
Canis lupus familiaris (dog) : DUSP3 (dual specificity phosphatase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dusp3 (dual specificity phosphatase 3)
Sus scrofa (pig) : DUSP3 (dual specificity phosphatase 3)
Chlorocebus sabaeus (African green monkey) : DUSP3 (dual specificity phosphatase 3)
Heterocephalus glaber (naked mole-rat) : Dusp3 (dual specificity phosphatase 3)
more info ...
Related Pseudogenes: AC136896.1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1743,766,125 - 43,778,977 (-)EnsemblGRCh38hg38GRCh38
GRCh381743,766,125 - 43,778,977 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371741,843,489 - 41,856,368 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361739,199,015 - 39,211,872 (-)NCBINCBI36hg18NCBI36
Build 341739,199,015 - 39,211,872NCBI
Celera1738,551,496 - 38,564,369 (-)NCBI
Cytogenetic Map17q21.31NCBI
HuRef1737,607,587 - 37,620,460 (-)NCBIHuRef
CHM1_11742,079,099 - 42,091,978 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on DUSP3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345861
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.